The method described in this patent can predict the efficacy of vaccines against avian infectious bronchitis virus (IBV), without the use of experimental infections.
Currently, the control of IBV in poultry farming is based on the use of attenuated vaccines. Cross protection is often insufficient and vaccines must be accurately chosen and kept up to date according to the local scenario.
The present invention is based on the development of an algorithms which, starting from the knowledge of a specific trait of the viral genome, allows you to obtain quickly and at low cost the information necessary for choosing the most suitable vaccine strain for the local context.
