The endovascular treatment of aortic arch aneurysms allows to exclude an aneurysm, ensuring proximal and distal seeling and preventing any endoleaks, sustained by supra-aortic trunks. This endograft is dedicated to aortic arch aneurysm treatment. Its aims to favor a less invasive approach compared to the ‘classical’ more risky, open reconstruction and to reduce some problems with the aortic arch endografts, currently in use. This fenestrated endograft is equipped with an endobag and is specifically designed for the aortic arch segment. Currently the endografts used to treat the aneurysms of the aortic arch are an adaptation, which are not always safe, of other endografts used to isolate Abdominal Aortic or Descending Thoracic Aorta aneurysms. The complex anatomy of the aortic arch requires the development of a specific endograft able to overcome the limitations of the endogafts currently in use.
This patented endograft, fenestrated and equipped with an endobag, is able to reduce the risks of brain embolisms, because it doesn’t require the release of other cover stents at supraortic artery levels and reduces the risk of endoleaks, thanks to the presence of an endobag that occupies all possible space, between the prosthetic and aortic walls: being mono-modular, few steps are necessary for its release. Therefore, this invention provides a safer graft for the endovascular repair of aortic arch aneurysms, avoiding the risks associated with “classic” open surgery or the use of current multi-modular fenestrated endoprografts, which are unable to adapt perfectly to the specific conformation of the anatomy of this aortic segment.

TRL 4 / 9



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PoC@Unipd project

With the aim of supporting the competitiveness of businesses by enhancing industrial properties, the Ministry for Economic Development (MISE) has published a call for the establishment of patent enhancement programs, through funding of Proof of Concept (PoC) projects by Italian Universities, Public Research Institutions (EPR), and Scientific Institutions for Research, Hospital and Healthcare (IRCS).

Purpose of the call is establishing TRL (Technology Readiness Level) enhancement paths for technologies patented during academic research, and create the conditions to turn them into strategic opportunities for the business world.

After careful examination of the project proposals received by the Ministry Evaluation Committee, the University of Padua ranked 4th in the classification, and was authorized to develop 9 PoC projects.

The projects were selected by the University through an internal call and the program took the first steps in February 2021. From that moment on, the PoC Team started to work to validate the relevant technologies. The academic work team has been flanked by an external Expert Committee, comprising top scientific and professional resources (investors and entrepreneurs), capable of providing a respected standpoint on all strategic and planning choices.

UniSMART – Fondazione Università di Padova was tasked with managing the enhancement of the results of 9 projects, through its highly qualified, innovation-oriented staff, in the different PoC project sectors.

  • Walking simulator for prosthetic device testing

    The object of the patent is a walking simulator capable of reproducing the kinematics and kinetics of the leg during a wide variety of gait-related tasks (level/inclined/stairs walking...) and walking conditions (uneven/wet/muddy terrains...), with the purpose of collecting meaningful data[...]

  • Use of small molecules to rescue folding defective proteins

    The use of CFTR (cystic fibrosis transmembrane conductance regulator) correctors for the treatment of rare and devastating genetic muscular diseases, namely sarcoglycanopathies and Brody myopathy, is the object of this invention. Sarcoglycanopathies and Brody myopathy are rare inherited striated muscle[...]

  • Method for controlling the delivery of insulin

    Currently diabetic patients wear sensors that track and communicate their glucose levels, as well as alarm when they go out of range. The patient, if aware and shrewd, then injects the correct amount of insulin based on the glycemic level[...]

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