Glioblastoma (GBM) is the most common brain cancer among adults and patients and has an overall survival (OS) of 15 months. Nowadays brain tumours are not taken in evaluation in relation to the brain area in which they are located. Recent studies have demonstrated that their prognosis is not independent of the structural organisation of the brain: in particular, white matter fibres disconnection degrees can be considered as a prognosis biomarker. The present invention refers to an algorithm for determining a new prognostic index of a brain tumour and it has been already implemented in a software with a user-friendly graphical interface (GUI). The method provides an indirect estimate of the damage that the tumour causes in patients, through data analysis comparison. The prognostic index, together with OS proves how different tumours in different brain areas can cause a peculiar damage, affecting the patient’s prognosis.

TRL (Technology Readiness Level)

TRL 4 / 9

Inventors

Maurizio
Corbetta

Alessandro
Salvalaggio

Lorenzo
Pini

Download the brochure

  • Method for controlling the delivery of insulin

    Currently diabetic patients wear sensors that track and communicate their glucose levels, as well as alarm when they go out of range. The patient, if aware and shrewd, then injects the correct amount of insulin based on the glycemic level[...]

  • Alternative arthropathy treatment

    The combined effect of the BPI protein (bactericidal/permeability-increasing protein) and hyaluronic acid has proven effective for the treatment of arthropathies. It may integrate or replace current anti-inflammatory therapies that at times have serious side effects. This pharmaceutical combination that contains[...]

  • PERFUSE: peripheral arterial perfusion cannula

    Extracorporeal circulation is the only method used during cardiovascular surgery and requires the use of cannulas which are inserted into the arterial vessels: the cannulas on the market are unidirectional and only allow blood flow towards the heart. Especially in[...]

Subscribe to newsletter

Follow the activities promoted by UniSMART Foundation