Fungi of the genus Trichoderma produce peptaibols, secondary metabolites that are part of their defence system against other microorganisms. Such compounds are known for their ability to protect plants from parasites by stimulating the plant’s defence mechanisms and because of their antimicrobial properties.
This patent covers the synthetic analogues of the natural trichogin peptide GA IV and their use as biopesticides against Plasmopara viticola, Botrytis cinerea, Penicillium italicum, Penicillium digitatum, Penicillium expansum, Fusarium graminearum e Pyricularia oryzae. Compared to other peptaibol based products on the market, which are generally non purified natural extracts, this biocompatible product is much more effective, as well as being soluble in water and stable in sunlight.

TRL 4 / 9

Inventors

Marta
De
Zotti

Francesco
Favaron

Luca
Sella

Download the brochure

PoC@Unipd project

With the aim of supporting the competitiveness of businesses by enhancing industrial properties, the Ministry for Economic Development (MISE) has published a call for the establishment of patent enhancement programs, through funding of Proof of Concept (PoC) projects by Italian Universities, Public Research Institutions (EPR), and Scientific Institutions for Research, Hospital and Healthcare (IRCS).

Purpose of the call is establishing TRL (Technology Readiness Level) enhancement paths for technologies patented during academic research, and create the conditions to turn them into strategic opportunities for the business world.

After careful examination of the project proposals received by the Ministry Evaluation Committee, the University of Padua ranked 4th in the classification, and was authorized to develop 9 PoC projects.

The projects were selected by the University through an internal call and the program took the first steps in February 2021. From that moment on, the PoC Team started to work to validate the relevant technologies. The academic work team has been flanked by an external Expert Committee, comprising top scientific and professional resources (investors and entrepreneurs), capable of providing a respected standpoint on all strategic and planning choices.

UniSMART – Fondazione Università di Padova was tasked with managing the enhancement of the results of 9 projects, through its highly qualified, innovation-oriented staff, in the different PoC project sectors.

  • 3D MICRO-ERT FOR AGRICULTURE

    Three-dimensional micro tomography analysis of electrical resistivity (Micro-ERT 3D) can detail soil moisture content and can monitor areas where uptake occurs near a plant's root system. This patent improves the 3D Micro-ERT to achieve high levels of measurement accuracy. In[...]

  • Vaccine efficacy prediction in poultry farming

    The method described in this patent can predict the efficacy of vaccines against avian infectious bronchitis virus (IBV), without the use of experimental infections. Currently, the control of IBV in poultry farming is based on the use of attenuated vaccines.[...]

  • Use of small molecules to rescue folding defective proteins

    The use of CFTR (cystic fibrosis transmembrane conductance regulator) correctors for the treatment of rare and devastating genetic muscular diseases, namely sarcoglycanopathies and Brody myopathy, is the object of this invention. Sarcoglycanopathies and Brody myopathy are rare inherited striated muscle[...]

Subscribe to newsletter

Follow the activities promoted by UniSMART Foundation