• MERCURIO – Communication system based on multipole-phase division

    The patent discloses a spatial division multiplexing optical communication system comprising optical devices for the multiplexing and demultiplexing of beams endowed with different multipole phases. This invention proposes an innovative and efficient solution to increase the transmission capacity of the[...]

  • siRNAEEC – Novel treatment to mitigate the Ectrodactyly-Ectodermal dysplasia- Clefting (EEC) associated blindness

    The Ectrodactyly-Ectodermal dysplasia-Clefting (EEC) syndrome is a rare genetic disorder due to mutations in the p63 gene and characterized by limb defects, orofacial clefting, ectodermal dysplasia, and ocular surface defects that lead to the loss of vision. Currently no specific[...]

  • TEC-PROMEST – Protein extraction method for diagnostics

    Accurate diagnosis and typing of Amyloidosis, a group of diseases where the abnormal protein, called amyloid, builds-up in the organs and interferes with their normal function, is of paramount importance in order to determine the appropriate therapeutic intervention. Current methods[...]

  • CuRE – Copper complexes as novel anticancer agents

    Although platinum-based drugs, such as cisplatin, have achieved great success in cancer treatment and are presently enclosed in the majority of clinical protocols for the management of solid malignancies, their use are associated with significant drawbacks such as severe toxic[...]

  • TREM2MICROENGINES – Novel Regulated Promoter for Gene Therapy

    Neuroinflammation, characterized by microglial cell-activation, plays a major role in the pathogenesis and progression of multiple neurodegenerative diseases, such as Lysosomal Storage Disorders and Alzheimer’s, severe human conditions currently lacking an effective treatment. Ex vivo gene therapy based on genetically[...]

  • INSERT – SerpinB3 inhibitor for tumor treatment

    Expression of SerpinB3, a member of serine-protease inhibitor family, is associated with the carcinogenesis process as it determines resistance to apoptosis, induces cell proliferation and greater cell invasiveness. Furthermore, it leads to impaired immune surveillance and reduced chemosensitivity. Recent studies[...]

  • RAPID-AFM1 – Rapid detection of Aflatoxin M1 in milk

    The present invention relates to a method and a device useful for directly and rapidly quantifying the presence in milk of Aflatoxin M1, a carcinogenic mycotoxin deriving from Aflatoxin B1. In particular conditions of humidity or high temperatures, some vegetable[...]

  • CO2 SUP – Food preservation with supercritical CO2

    This invention uses supercritical carbon dioxide to pasteurize food, at temperature and pressure conditions that do not alter its structure or flavour. The process allows for longer product shelf life since it reduces the presence of bacteria in fresh food[...]